
Dr J.S. Vyle
BSc (University of Birmingham), 1986
PhD (University of Liverpool), 1989
Lecturer in Organic Chemistry
Tel: + 44 (0) 28 9097 5485
Fax: + 44 (0) 28 9097 6524
E-mail: j.vyle@qub.ac.uk
A novel structural class of photoswitchable oligonucleotide
EE Smith, JN McClean, LA Cooke, J-L Duprey, M McCourt, MM Fabani, JHR Tucker and JS Vyle 2007,
Tetrahedron Letters, 48, 6569-6572 DOI: 10.1016/j.tetlet.2007.07.028
Link to Journal site: doi:10.1016/j.tetlet.2007.07.028
Analysis of DNA processing reactions in bacterial conjugation by using suicide oligonucleotides
B Gonzalez-Perez, M Lucas, LA Cooke, JS Vyle, F de la Cruz,* and G Moncalián 2007 The EMBO Journal, 26, 3847–3857 DOI:10.1038/sj.emboj.7601806
Link to Journal site
http://www.nature.com/emboj/journal/v26/n16/full/7601806a.html
Preparation of Potential Cell-Permeant Nucleoside-2',3'-Cyclic Phosphate Precursors
S Battaggia, EE Smith; JS Vyle 2007 Nucleosides, Nucleotides and Nucleic Acids, 26, 245 - 254 DOI: 10.1080/15257770701257236
Link to Journal site
http://www.informaworld.com/smpp/title~content=t713597286~db=all
Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe
N Moran, DM Bassani, J-P Desvergne, S Keiper, PAS Lowden, JS Vyle and JHR Tucker 2006 Chemical Communications, 5003 - 5005 DOI: 10.1039/b611650g
Link to Journal site http://www.rsc.org/ej/CC/2006/b611650g.pdf

Reversible Photocontrol of Deoxyribozyme-Catalyzed RNA Cleavage under Multiple-Turnover Conditions
S Keiper, JS Vyle, 2006, Angewandte Chemie International Edition, 45, 3306 - 3309. LINK TO PDF

Solid-phase synthesis of terminal oligonucleotide-phosphoramidate conjugates. LA Cooke, C Frauendorf, MA Gîlea, SC Holmes, JS Vyle, 2006,
Tetrahedron Letters, 47, 719-722. LINK TO JOURNAL SITE PDF (140 K)
